Demo Run Load demo data Job name: Email (links for result will be sent to your email):

Upload your GWAS data Select data type: SNP    CNV    Gene GWAS file:    -logarithm transformation (necessary ONLY for P-value data)

Select mapping rules of SNPs->genes 500kb upstream and downstream of gene 100kb upstream and downstream of gene 20kb upstream and downstream of gene 5kb upstream and downstream of gene within gene functional SNP (nonsynonymous, stop gained/lost, frame shift, essential splice site, regulatory region)

Gene set database canonical pathways    GO biological process    GO molecular function    GO cellular component    OR upload your own gene sets file:   Options for gene set database Limit gene sets by keyword (e.g. immune). The keyword can be gene name (e.g. CD4) Keyword: include    exclude Number of genes in gene set     Minimum (typical 5-20): Maximum (typical 200-inf): Mask MHC/xMHC region NO    mask MHC    mask xMHC