Pathway/Gene set name
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Description
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Manhattan plot
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P-value
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FDR
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Significant genes/Selected genes/All genes
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hsa00970
hsa00970
More...
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< 0.001
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0.0020
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16/34/470
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Genes annotated by t......
Genes annotated by the GO term GO:0045765. Any process that modulates the frequency, rate or extent of angiogenesis.
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< 0.001
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0.03425
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10/21/26
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hsa00030
hsa00030
More...
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< 0.001
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0.040400002
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9/20/470
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Genes annotated by t......
Genes annotated by the GO term GO:0007417. The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
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< 0.001
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0.040666666
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51/97/122
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Genes annotated by t......
Genes annotated by the GO term GO:0005178. Interacting selectively with an integrin.
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< 0.001
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0.059833333
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16/25/30
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Genes annotated by t......
Genes annotated by the GO term GO:0051348. Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
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< 0.001
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0.061
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11/29/35
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Genes annotated by t......
Genes annotated by the GO term GO:0051093. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
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< 0.001
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0.077285714
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52/168/193
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CXCR4 Signaling Path......
CXCR4 Signaling Pathway
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0.0030
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0.16769566
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13/23/24
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Genes annotated by t......
Genes annotated by the GO term GO:0046930. Any small opening in a membrane that allows the passage of gases and/or liquids.
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0.0060
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0.17077273
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10/33/34
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Genes annotated by t......
Genes annotated by the GO term GO:0006302. The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
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0.0080
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0.17137499
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8/20/22
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Genes annotated by t......
Genes annotated by the GO term GO:0051338. Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
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0.0030
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0.17273684
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41/139/157
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hsa00480
hsa00480
More...
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0.012
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0.17325
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10/38/470
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Genes annotated by t......
Genes annotated by the GO term GO:0004879. A ligand-dependent receptor found in the nucleus of the cell.
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0.0030
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0.17445001
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12/24/25
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Genes annotated by t......
Genes annotated by the GO term GO:0043086. Any process that stops or reduces the activity of an enzyme.
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0.0050
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0.17684
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19/56/69
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Genes annotated by t......
Genes annotated by the GO term GO:0003704. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II.
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0.0040
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0.17823529
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10/30/35
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Genes annotated by t......
Genes annotated by the GO term GO:0032403. Interacting selectively with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
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0.0030
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0.17842858
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22/47/54
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Genes annotated by t......
Genes annotated by the GO term GO:0044453. Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells.
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0.0080
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0.18094444
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11/38/40
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hsa00010
hsa00010
More...
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0.0070
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0.18178572
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16/52/470
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Genes annotated by t......
Genes annotated by the GO term GO:0003823. Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
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0.0030
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0.1822
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9/21/28
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Genes annotated by t......
Genes annotated by the GO term GO:0000793. A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
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0.0090
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0.18337038
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11/27/33
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Genes annotated by t......
Genes annotated by the GO term GO:0045859. Any process that modulates the frequency, rate or extent of protein kinase activity.
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0.0050
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0.1842069
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39/133/151
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Genes annotated by t......
Genes annotated by the GO term GO:0019748. The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
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0.0090
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0.18607691
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9/23/25
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Genes annotated by t......
Genes annotated by the GO term GO:0007059. The process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
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0.0090
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0.1860909
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10/30/31
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Genes annotated by t......
Genes annotated by the GO term GO:0031667. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
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0.011
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0.18638462
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8/27/29
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Genes annotated by t......
Genes annotated by the GO term GO:0006916. A process which directly inhibits any of the steps required for cell death by apoptosis.
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0.0030
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0.19157143
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29/103/115
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Genes annotated by t......
Genes annotated by the GO term GO:0043549. Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
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0.0070
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0.1945
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39/135/153
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Genes annotated by t......
Genes annotated by the GO term GO:0009991. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
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0.0060
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0.19716667
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9/30/33
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Genes annotated by t......
Genes annotated by the GO term GO:0005829. That part of the cytoplasm that does not contain membranous or particulate subcellular components.
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0.0020
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0.20269999
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58/174/202
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Genes annotated by t......
Genes annotated by the GO term GO:0043069. Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
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0.0020
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0.2043871
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34/131/148
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Genes annotated by t......
Genes annotated by the GO term GO:0005525. Interacting selectively with GTP, guanosine triphosphate.
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0.012
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0.21697222
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11/39/46
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hsa01040
hsa01040
More...
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0.0030
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0.217
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10/21/470
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hsa04920
hsa04920
More...
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0.0090
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0.21777144
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25/67/470
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PKC-catalyzed phosph......
PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase
More...
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0.0030
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0.21900001
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15/28/31
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hsa05322
hsa05322
More...
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0.0080
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0.22021052
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18/50/470
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Genes annotated by t......
Genes annotated by the GO term GO:0043066. Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis.
More...
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0.0050
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0.22332352
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34/130/147
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Thrombin signaling a......
Thrombin signaling and protease-activated receptors
More...
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0.0030
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0.22378378
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18/34/37
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Genes annotated by t......
Genes annotated by the GO term GO:0017016. Interacting selectively with any member of the Ras superfamily of monomeric GTPases.
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0.014
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0.22385105
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9/22/24
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Genes annotated by t......
Genes annotated by the GO term GO:0005635. The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
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0.0060
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0.22396874
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20/65/70
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Genes annotated by t......
Genes annotated by the GO term GO:0008277. Any process that modulates the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
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0.0040
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0.22455555
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10/20/23
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Genes annotated by t......
Genes annotated by the GO term GO:0019901. Interacting selectively with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
More...
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0.0090
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0.22547826
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20/56/62
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Genes annotated by t......
Genes annotated by the GO term GO:0007420. The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
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0.011
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0.22737779
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20/39/51
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TRANSFERASE ACTIVITY TRANSFERRING ALKYL OR ARYLOTHER THAN METHYLGROUPS
View Detail
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Genes annotated by t......
Genes annotated by the GO term GO:0016765. Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
More...
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0.014
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0.22867501
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8/24/30
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hsa01510
hsa01510
More...
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0.01
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0.22893181
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14/40/470
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Genes annotated by t......
Genes annotated by the GO term GO:0051082. Interacting selectively with an unfolded protein.
More...
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0.014
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0.22930768
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9/38/41
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Genes annotated by t......
Genes annotated by the GO term GO:0030695. Modulates the rate of GTP hydrolysis by a GTPase.
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0.0070
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0.22995123
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46/102/117
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Genes annotated by t......
Genes annotated by the GO term GO:0012505. A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
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0.0060
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0.23130953
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57/189/212
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Genes annotated by t......
Genes annotated by the GO term GO:0007565. The physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
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0.0080
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0.23193751
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13/34/52
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Genes annotated by t......
Genes annotated by the GO term GO:0030036. A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
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0.0080
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0.23244186
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36/90/104
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