Pathway/Gene set name
|
Description
|
Manhattan plot
|
P-value
|
FDR
|
Significant genes/Selected genes/All genes
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042923. Interacting selectively and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).
More...
|
|
< 0.001
|
0.0010
|
10/20/23
|
|
hsa04020
hsa04020
More...
|
|
< 0.001
|
0.0055
|
72/146/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005070. Interacting selectively and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
More...
|
|
< 0.001
|
0.023333333
|
18/34/43
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0045321. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
More...
|
|
< 0.001
|
0.0255
|
19/51/67
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0045087. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
More...
|
|
0.0010
|
0.028333334
|
9/20/23
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022843. Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion.
More...
|
|
< 0.001
|
0.029375
|
32/60/66
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0060090. The binding activity of a molecule that brings together two or more molecules, permitting those molecules to function in a coordinated way.
More...
|
|
< 0.001
|
0.031285714
|
21/39/49
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005262. Catalysis of facilitated diffusion of an calcium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
More...
|
|
< 0.001
|
0.033
|
20/30/33
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0030674. Interacting selectively with two or more protein molecules, or a protein and another macromolecule or complex, simultaneously, thereby physically linking the bound proteins or complexes to each other.
More...
|
|
0.0010
|
0.033999998
|
21/50/59
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007586. The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
More...
|
|
< 0.001
|
0.03690909
|
14/36/43
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0046873. Catalysis of the transfer of metal ions from one side of a membrane to the other.
More...
|
|
0.0010
|
0.037384614
|
59/130/145
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0046649. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
More...
|
|
< 0.001
|
0.038
|
16/46/60
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0001653. Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
More...
|
|
< 0.001
|
0.039444443
|
15/40/50
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005261. Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
More...
|
|
< 0.001
|
0.040357143
|
49/107/118
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0048037. Interacting selectively with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
More...
|
|
0.0010
|
0.0416875
|
10/20/22
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006446. Any process that modulates the frequency, rate or extent of translational initiation.
More...
|
|
0.0030
|
0.042866666
|
9/26/31
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007565. The physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
More...
|
|
0.0020
|
0.04422222
|
15/39/52
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006869. The directed movement of lipids into, out of, within or between cells. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
More...
|
|
0.0010
|
0.045157894
|
9/23/28
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0043623. The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
More...
|
|
0.0020
|
0.046117645
|
11/28/33
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022832. Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
More...
|
|
< 0.001
|
0.04635
|
32/66/73
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0001775. A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
More...
|
|
0.0010
|
0.050956525
|
20/58/75
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051130. Any process that activates or increases the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
More...
|
|
0.0010
|
0.051545452
|
15/33/35
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007005. A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphology and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
More...
|
|
< 0.001
|
0.053333335
|
11/37/48
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0030384. The chemical reactions and pathways involving phosphoinositides, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of inositol. They are important constituents of cell membranes.
More...
|
|
0.0030
|
0.05584
|
10/24/28
|
|
hsa04070
hsa04070
More...
|
|
< 0.001
|
0.0565
|
31/69/470
|
|
hsa05340
hsa05340
More...
|
|
0.0020
|
0.057166666
|
10/27/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005911. A specialized region of connection between two cells including but not limited to gap junctions, desmosomes, and tight junctions, but excluding direct cytoplasmic junctions such as ring canals.
More...
|
|
< 0.001
|
0.060814813
|
23/52/65
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0044429. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
More...
|
|
0.0040
|
0.066785716
|
23/110/141
|
|
hsa00562
hsa00562
More...
|
|
0.0020
|
0.0694
|
18/42/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042592. The biological processes involved in the maintenance of an internal equilibrium.
More...
|
|
< 0.001
|
0.069758624
|
52/169/201
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006413. The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
More...
|
|
0.0060
|
0.07874194
|
10/30/39
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0008146. Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.
More...
|
|
0.0040
|
0.08018919
|
11/24/27
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0045727. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
More...
|
|
0.0020
|
0.08084375
|
9/26/34
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0046474. The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
More...
|
|
0.0080
|
0.080971435
|
8/24/30
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042165. Interacting selectively with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
More...
|
|
0.0020
|
0.08104878
|
15/47/53
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0008092. Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
More...
|
|
0.0010
|
0.081727274
|
58/141/158
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0030054. A specialized region of connection between two cells or between a cell and the extracellular matrix.
More...
|
|
0.0010
|
0.08185
|
28/66/80
|
|
hsa04912
hsa04912
More...
|
|
< 0.001
|
0.08226471
|
33/84/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022836. Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
More...
|
|
0.0010
|
0.082333334
|
46/109/121
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0001584. A G-protein coupled receptor that is structurally/functionally related to the rhodopsin receptor.
More...
|
|
0.0050
|
0.08302564
|
34/103/131
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0019932. A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.
More...
|
|
< 0.001
|
0.0845
|
44/123/146
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022613. The cellular process by which a complex containing RNA and proteins, is synthesized, aggregates, and bonds together.
More...
|
|
0.0090
|
0.08545238
|
16/62/79
|
HEMATOPOIETIN INTERFERON CLASSD200 DOMAIN CYTOKINE RECEPTOR BINDING
View Detail
|
Genes annotated by t......
Genes annotated by the GO term GO:0005126.
More...
|
|
0.014
|
0.08883721
|
5/26/29
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006959. An immune response mediated through a body fluid.
More...
|
|
0.0040
|
0.092954546
|
11/26/31
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042277. Interacting selectively with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
More...
|
|
0.0050
|
0.09374468
|
23/69/82
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007010. A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
More...
|
|
0.0040
|
0.09467392
|
62/183/205
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006650. The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
More...
|
|
0.0070
|
0.09506667
|
13/36/43
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0008324. Catalysis of the transfer of cation from one side of the membrane to the other.
More...
|
|
0.0020
|
0.095270835
|
72/187/211
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0002684. Any process that activates or increases the frequency, rate, or extent of an immune system process.
More...
|
|
0.0030
|
0.0955
|
14/42/51
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006816. The directed movement of calcium (Ca) ions into, out of, within or between cells.
More...
|
|
0.0030
|
0.095714286
|
13/23/27
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0000003. The production by an organism of new individuals that contain some portion of their genetic material inherited from that organism.
More...
|
|
0.0020
|
0.098882355
|
52/192/261
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005625. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water.
More...
|
|
0.0050
|
0.10444231
|
35/130/160
|
|
Links between Pyk2 a......
Links between Pyk2 and Map Kinases
More...
|
|
0.0080
|
0.11281132
|
12/25/31
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042110. The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
More...
|
|
0.0080
|
0.11314815
|
11/36/44
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0002682. Any process that modulates the frequency, rate, or extent of an immune system process.
More...
|
|
0.0060
|
0.11742373
|
16/52/67
|
|
hsa04916
hsa04916
More...
|
|
0.0010
|
0.11765455
|
32/86/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051094. Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
More...
|
|
0.0070
|
0.11778948
|
57/183/215
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0016042. The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
More...
|
|
0.011
|
0.11839655
|
10/33/37
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005216. Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
More...
|
|
0.0030
|
0.11853571
|
52/131/147
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0030594. Combining with a neurotransmitter to initiate a change in cell activity.
More...
|
|
0.011
|
0.124000005
|
14/45/50
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007409. Generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells.
More...
|
|
0.0020
|
0.1245238
|
20/35/43
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0048878. The biological processes involved in the maintenance of an internal equilibrium of a chemical.
More...
|
|
0.0090
|
0.12453333
|
35/126/150
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0016337. The attachment of one cell to another cell via adhesion molecules.
More...
|
|
0.0070
|
0.12490625
|
30/76/86
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0050863. Any process that modulates the frequency, rate or extent of T cell activation.
More...
|
|
0.012
|
0.124951616
|
8/23/28
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051128. Any process that modulates the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
More...
|
|
0.0040
|
0.12633847
|
38/109/123
|
|
hsa04640
hsa04640
More...
|
|
0.0080
|
0.12643479
|
24/69/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051098. Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
More...
|
|
0.0090
|
0.12686765
|
13/46/58
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007600. The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
More...
|
|
0.013
|
0.12835822
|
52/157/190
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0043086. Any process that stops or reduces the activity of an enzyme.
More...
|
|
0.0070
|
0.12901516
|
18/57/69
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051240. Any process that activates or increases the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
More...
|
|
0.013
|
0.13057144
|
17/52/66
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0000904. The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
More...
|
|
0.0070
|
0.13422078
|
22/41/49
|
|
hsa00260
hsa00260
More...
|
|
0.014
|
0.13581578
|
10/32/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005759. The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty-acid oxidation.
More...
|
|
0.011
|
0.13637333
|
9/42/46
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0031980. The volume enclosed by the mitochondrial inner membrane.
More...
|
|
0.011
|
0.13637333
|
9/42/46
|
|
hsa03050
hsa03050
More...
|
|
0.026
|
0.13839726
|
5/21/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042157. The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids.
More...
|
|
0.02
|
0.13884722
|
8/28/33
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0046489. The chemical reactions and pathways resulting in the formation of phosphoinositides, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of inositol.
More...
|
|
0.019
|
0.13887323
|
7/20/24
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0009887. Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process by which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
More...
|
|
0.01
|
0.14360256
|
39/124/144
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005615. That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
More...
|
|
0.011
|
0.1649277
|
54/200/239
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022603. Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
More...
|
|
0.01
|
0.1652125
|
11/21/24
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0019725. The processes involved in the maintenance of an internal equilibrium at the level of the cell.
More...
|
|
0.016
|
0.16596341
|
36/116/141
|
|
hsa04514
hsa04514
More...
|
|
0.0080
|
0.1662469
|
44/114/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051082. Interacting selectively with an unfolded protein.
More...
|
|
0.025
|
0.16726582
|
9/39/41
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0016044. A process that is carried out at the cellular level which results in the formation, arrangement of constituent parts, or disassembly of membranes inside and surrounding the cell.
More...
|
|
0.014
|
0.17972942
|
42/120/133
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005938. The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
More...
|
|
0.02
|
0.18037209
|
14/36/38
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0048646. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
More...
|
|
0.01
|
0.18067816
|
18/46/56
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006944. The joining of two lipid bilayers to form a single membrane.
More...
|
|
0.013
|
0.18085715
|
11/28/28
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0030001. The directed movement of metal ions, any metal ion with an electric charge, into, out of, within or between cells.
More...
|
|
0.017
|
0.1963587
|
41/103/116
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051249. Any process that modulates the frequency, rate or extent of lymphocyte activation.
More...
|
|
0.023
|
0.19713484
|
8/27/35
|
|
BCR Signaling Pathwa......
BCR Signaling Pathway
More...
|
|
0.023
|
0.1971613
|
12/29/37
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0000313. A ribosome contained within a subcellular organelle.
More...
|
|
0.029
|
0.19721979
|
4/20/22
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005761. A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
More...
|
|
0.029
|
0.19721979
|
4/20/22
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022414. A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
More...
|
|
0.017
|
0.19765626
|
33/117/159
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022838. Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
More...
|
|
0.014
|
0.199
|
52/137/154
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051248. Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
More...
|
|
0.021
|
0.19915909
|
11/39/47
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0044242. The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
More...
|
|
0.026
|
0.20006123
|
9/30/34
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051640. The processes by which an organelle is transported to, and/or maintained in, a specific location.
More...
|
|
0.03
|
0.20025532
|
7/20/24
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051090. Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
More...
|
|
0.02
|
0.20082474
|
9/30/40
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022890. Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
More...
|
|
0.022
|
0.20534286
|
17/47/57
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0010033. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
More...
|
|
0.018
|
0.20534863
|
10/25/30
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0005764. Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
More...
|
|
0.021
|
0.20537001
|
16/47/60
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0000323. A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
More...
|
|
0.021
|
0.20537001
|
16/47/60
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0003779. Interacting selectively with monomeric or multimeric forms of actin, including actin filaments.
More...
|
|
0.013
|
0.20562264
|
29/69/76
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051246. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
More...
|
|
0.023
|
0.20575489
|
37/147/171
|
|
hsa04720
hsa04720
More...
|
|
0.023
|
0.20585436
|
26/60/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0032268. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
More...
|
|
0.024
|
0.20616347
|
34/138/160
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0030029. Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
More...
|
|
0.016
|
0.20639604
|
37/105/114
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0044248. The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
More...
|
|
0.027
|
0.20694445
|
48/185/209
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0022618. The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.
More...
|
|
0.029
|
0.20711215
|
12/52/64
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0031570. Any cell cycle checkpoint that delays or arrests cell cycle progression in response to changes in DNA structure.
More...
|
|
0.031
|
0.20877273
|
7/20/23
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051101. Any process that modulates the frequency, rate or extent of DNA binding, selective interaction with deoxyribonucleic acid.
More...
|
|
0.028
|
0.21813513
|
10/36/47
|
|
CTCF: First Multival......
CTCF: First Multivalent Nuclear Factor
More...
|
|
0.03
|
0.2226875
|
7/20/23
|
|
hsa00790
hsa00790
More...
|
|
0.035
|
0.22351328
|
10/33/470
|
|
hsa00600
hsa00600
More...
|
|
0.039
|
0.22735965
|
11/29/470
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0000775. The central region of a chromosome that includes the centromere and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
More...
|
|
0.03
|
0.22834782
|
9/28/31
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051704. The processes by which an organism has an effect on another organism of the same or different species.
More...
|
|
0.035
|
0.22912712
|
34/131/162
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0043235. Any protein group composed of two or more subunits, which may or may not be identical, which undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
More...
|
|
0.025
|
0.22961538
|
21/53/56
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0019933. A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
More...
|
|
0.02
|
0.23043966
|
21/55/65
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0019748. The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
More...
|
|
0.039
|
0.23420492
|
8/23/25
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0007276. The generation and maintenance of gametes. A gamete is a haploid reproductive cell.
More...
|
|
0.03
|
0.23553719
|
22/84/113
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0042770. A cascade of processes induced by the detection of DNA damage within a cell.
More...
|
|
0.037
|
0.23620833
|
10/29/35
|
TRANSFERASE ACTIVITY TRANSFERRING SULFUR CONTAINING GROUPS
View Detail
|
Genes annotated by t......
Genes annotated by the GO term GO:0016782. Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).
More...
|
|
0.034
|
0.23696639
|
11/28/31
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0016564. Any transcription regulator activity that prevents or downregulates transcription.
More...
|
|
0.028
|
0.23885366
|
37/123/148
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006508. The hydrolysis of a peptide bond or bonds within a protein.
More...
|
|
0.027
|
0.239512
|
46/154/188
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0051129. Any process that stops, prevents or reduces the frequency, rate or extent of the processes involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
More...
|
|
0.034
|
0.23958065
|
7/22/27
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0009617. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
More...
|
|
0.043
|
0.24788095
|
7/24/30
|
|
Genes annotated by t......
Genes annotated by the GO term GO:0006820. The directed movement of anions, atoms or small molecules with a net negative charge, into, out of, within or between cells.
More...
|
|
0.041
|
0.24955906
|
9/25/31
|